This paper summarizes gaps in the knowledge on uptake of preventive measures for Ebola Virus Disease (EVD), findings from studies that have been conducted on treatment and management of EVD, Barrier Analysis studies on behaviors related to EVD, and the lessons learned from these studies. This paper is primarily addressed to governments, NGOs, Faith-based organizations (FBOs), Community-based organization (CBOs), social and behavioral change professionals and frontline workers, researchers, and program planners. It is intended for anyone interested in understanding the key behavioral determinants that affect uptake of behaviors that help in the prevention, early treatment and management of EVD, other communicable diseases similar to EVD (e.g., Marburg Virus Disease), and diseases that are transmitted by some of the behaviors studied (e.g., hand washing with soap).